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In the case of TB, there is a very strong genetic basis of susceptibility to this bacterium, with resistance developing among the indigenous north American population after European colonization, owing to the high initial mortality and therefore rapid selection against susceptibility genes (Abel et al., 2018)
Observations are model-dependent and exploratory
We take the linear rate constant to be 4 M/hr, which gives a half-life of approximately 10 minutes, since absorption will be slower with pills and non-fasted state
The detoxification-induced siphoning of Cys could reduce the availability of Cys for skeletal muscle
It is safe, extensively studied in humans for decades without any adverse effects
10.1371/journal.pone.0007052 4 BachmairA.VarshavskyA
