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The relationship between thyroid function and metabolic health is bidirectional and complexthyroid hormones influence glucose metabolism and insulin sensitivity, while metabolic dysfunction can affect thyroid hormone conversion and action at the cellular level
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In SUSTAIN-3, 41.8% of patients with subcutaneous semaglutide had GI adverse effects, compared with 33.3% in exenatide once weekly ( For oral semaglutide, the data are similar
Fatigue (36.9%), headache (30.3%), and dizziness (25.9%) were similarly prevalent across all three studies, reaffirming the need for effective side effect management to optimize adherence
Side effects such as nausea, diarrhea, and constipation may occur, making the involvement of medical professionals paramount in directing effective, safe usage
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