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The exclusion criteria for this review would be all secondary literature and any original articles written and submitted in languages other than English
The same 2017 study referenced above reported the following side effects in some participants who received 250mg of oral glutathione:6 Pruritis (itching) Macular erythema (rash-like red patches on the skin) Red spots on the skin Tiredness Transaminitis (high liver enzyme levels in the blood) Additionally, specific glutathione supplements may pose more safety concerns than others
Vitamin B12 toxicity from supplements is extremely rare because it is water-soluble and excess amounts are excreted through urine
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That is not a safe assumption
Natural Remedies Natural skin lightening remedies, such as lemon juice and turmeric, can provide mild results
