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While both medications reduce hunger and promote sustainable weight loss, tirzepatide activates an additional hormone pathway (GIP) that may drive stronger metabolic changes

Tirzepatide activates both GLP-1 and GIP receptors, while semaglutide is GLP-1-only

it demands a nuanced understanding of potency, indication, and titration to avoid adverse effects and ensure therapeutic success

These peptides communicate with your pituitary gland, which is responsible for hormone regulation in the body

References Adams, B

However, they are typically recommended as part of a comprehensive weight management plan that includes a healthy diet and regular physical activity