But the timing
These patents do not prevent a generic manufacturer from filing an ANDA for the original approved indication, but they can prevent the generic from carving in the patented use to their label, and they can create prescriber-level inertia if the patented indication is the primary reason for prescribing
By activating GLP-1 receptors in the brain and digestive system, these medications significantly reduce appetite, increase feelings of fullness after meals, and help the body preferentially burn stored fat
A new study led by Mayo Clinic found that postmenopausal women receiving menopausal hormone therapy lost 35% more weight while taking tirzepatide, a Food and Drug Administration-approved drug for the treatment of overweight and obesity
The potential side effects of GLP-1 drugs are no fun: nausea, vomiting, fatigue, diarrhea, constipation
doi:10.1007/s00394-019-02123-0