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Some options may have contraindications, require clinician supervision, and may cause side effects
These effects can lead to weight loss, which can be an important part of managing diabetes
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As a seasoned vegan, Ive heard on multiple occasions I need to supplement vitamin B12 into my diet
The authors highlight biological plausibility, acknowledge limitations of retrospective administrative data, and call for randomized prospective trials to confirm causality and optimize treatment strategies
While the gastrointestinal effects (nausea, diarrhea, vomiting) are similar to other GLP-1 medications like Wegovy and Mounjaro, retatrutide has one unique finding: dysesthesia (abnormal touch sensations) in 20.9% of patients at the 12mg dose in TRIUMPH-4, and 12.5% at 12mg in the larger TRIUMPH-1 trial
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