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This means that hydroxycobalamin stays in the body for longer periods of time and can provide sustained levels of vitamin B12, which may be beneficial for individuals with severe or chronic vitamin B12 deficiency
The reason has to do with the sneaky way it suppresses vasopressin, the hormone that tells our kidneys to hold on to water
It is not intended as a standalone therapeutic dose for severe B12 deficiency, which would require separate supplementation at different intervals and doses under veterinary guidance
Journal of Physiology (Paris)
Program Options Our Tirzepatide/glycine/B12 programs are organized by vial size and dose, reflecting common titration stages
As of February 2026, both compounds have been reclassified as Category 1 peptides, meaning they may be compounded by licensed compounding pharmacies under a physician prescription
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