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57 Activation of GLP-1R in the kidney promotes sodium excretion and increases natriuresis, contributing to reduced plasma volume

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It is widely available through medical-supply retailers in the UK and EU under standard consumer-supply rules, in the same category as syringes, alcohol prep pads and other sterile single-purpose items

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Moreover, eight categories of psychiatric AEs, namely, nervousness (ROR = 1.97, 95% CI = 1.852.11), stress (ROR = 1.28, 95% CI = 1.191.38), eating disorder (ROR = 1.57, 95% CI = 1.401.77), fear of injection (ROR = 1.96, 95% CI = 1.602.40), sleep disorder due to general medical conditioninsomnia type (ROR = 2.01, 95% CI = 1.602.52), binge eating (ROR = 2.70, 95% CI = 1.754.16), fear of eating (ROR 3.35, 95% CI = 1.656.78), and self-induced vomiting (ROR = 3.77, 95% CI = 1.778.03), were defined as GLP-1 RA-related psychiatric AEs through disproportionality analysis