GLP-1 is a treatment that has been around for many years, even though its only just starting to be leveraged by the spa and aesthetician community
10.1155/2009/504625 43 GohY
Ipamorelin has been shown to stimulate GH secretion in vitro and in preclinical models with high receptor specificity, demonstrating minimal interaction with other endocrine pathways such as cortisol or prolactin release
Akimoto H, Negishi A, Oshima S, Wakiyama H, Okita M, Horii N, et al
But in general, turning a peptide (including GLP-1 or insulin) into an oral formulation means overcoming three major challenges: protecting the peptide from digestion in the stomach, improving absorption of the peptide via the gut, and slowing down the enzymatic breakdown and excretion of the peptide once it is in the blood
Enhanced Cognitive Behavioural Therapy for Patients With Eating Disorders: A Systematic Review. Curr Opin Psychiatry