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A subsequent larger RCT (n=72) confirmed these findings, showing improvements in gait speed, grip strength, exercise capacity, waist circumference, and systolic blood pressure (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]

Keep the lyophilized vial sealed and refrigerated until the day of reconstitution to maximize stability

This usually relates to rapid weight loss and reduced calorie/nutrient intake rather than direct medication effects

Wegovy pills may not be suitable if you : are under 18 are over 85 are pregnant or breastfeeding have had or have acute pancreatitis or pancreatitis are planning to try for a baby in the next 2 months you must stop semaglutide 2 months before trying to get pregnant are allergic to semaglutide have a severe digestive condition have severe kidney or liver problems Speak to your doctor before taking Wegovy pills if you have : type 2 diabetes, as some of your diabetes medication may need adjusting to reduce the chance of low blood sugar diabetic eye disease (retinopathy) sudden changes to your eyesight gastroparesis (delayed stomach emptying) had pancreatitis in the past are going to have surgery that requires a general anaesthetic or deep sedation low blood sugar (hypoglycaemia) severe heart failure diabetic eye problems Medications that can interact with the Wegovy pill Some medications may be unsuitable with Wegovy pills

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