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Hormonal shifts Body fat plays a role in hormone regulation by converting testosterone into estrogen, says Dr

GLP-1R-agonists regulate several inflammatory pathways, including cytokine production, oxidative stress, glucotoxicity, lypotoxicity and the recruitment of immune cells in several organs

Corticosteroids can help manage active inflammation and flares but should not be used as part of a long-term treatment plan because of their unwelcome side effects

Jiang et al., 2016)

The weight loss that comes with GLP-1 use is from both fat and muscle loss

Adequate protein serves two critical functions: it preserves lean muscle mass during rapid weight loss, and it supports satiety independent of the drug mechanism