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doi: 10.1016/j.xcrm.2021.100387 104 ArodaVRAberleJBardtrumLChristiansenEKnopFKGaberySet al
It can modulate sleep and wake functions
Comparison of GLP-/GIP dual agonists and GLP-1 GLP-1 and GIP, both major members of the incretin family, play a physiological role by binding and activating corresponding receptors to promote postprandial insulin secretion [125]
Pericyte-specific Kir6.1 knockout mice were generated by crossing tamoxifen-inducible NG2-Cre ERT2 knock-in mice 68 (kindly donated by Frank Kirchhoff, University of Saarland) and floxed (flx) Kir6.1 mice (kindly donated by Andrew Tinker, QMUL) to allow deletion of Kir6.1 in NG2-expressing pericytes after oral gavage of tamoxifen
JM expressed a preference for once-weekly injection, and, clinically, an agent with demonstrated cardiovascular risk reduction and efficacy for weight loss are indicated
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