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Some endogenous neuropeptides do cross via saturable transport systems, and there is speculation that DSIP may do so, but this has not been rigorously demonstrated for exogenously administered peripheral DSIP in humans

Byrne P, Demasi M, Jones M, Smith SM, OBrien KK, DuBroff R

The Chub-S7 cells (Nestle Research Center, Lausanne, Switzerland) were cultured in a mixture of DMEM/Hams F12 1 : 1 (Sigma) supplemented with 10% fetal bovine serum (Sigma)

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