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Side Effects Common side effects Nausea Diarrhea Vomiting Abdominal pain Fatigue Serious but less common side effects Pancreatitis Gallbladder disease (gallstones, cholecystitis) Kidney problems (from dehydration due to GI side effects) Potential increased risk of thyroid C-cell tumors (based on animal studies) Warnings and Precautions Contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2)

Read: User reviews mentioning dizziness Faster heart rate Tirzepatide raised resting heart rate by an average of 1 to 4 beats per minute across studies

It is not a substitute for the diagnosis or treatment of a medical condition

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One working hypothesis is that modulation of the gut microbes by the antimicrobial agent berberine could alter the composition of bacteria in the gut and lead to these observed effects

it can be either primary (idiopathic) or secondary to other skin conditions, penicillamine use, or premature birth