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additionally, a domain-specific assessment using the Cochrane Risk of Bias Tool (RoB 2) was also conducted and reported in Table 3 to provide a comprehensive appraisal

Analysis of Core Mechanism of Action To clarify the application value of 5amino1mq injection in metabolic research, it is first necessary to understand its core mechanism-the inhibition of NNMT, which affects the nicotinamide metabolic pathway, regulates NAD+ biosynthesis, and ultimately maintains metabolic homeostasis