Patients with one clearly defined injury need the local approach
Side effects may increase but remain manageable for most
Initial steps to consider: Document the changes : Keep a record of when changes began, their severity, and any other symptoms or life changes occurring simultaneously
But again, in the absence of clinical trials, we still don't know if and how they are working in humans
Therefore, a thorough medical history may be helpful for differential diagnosis, but the differentiation of physiological oral mucosal melanin hyperpigmentation from single or multiple melanotic macules based on medical history and on clinical and histological grounds may be impossible as they share the same clinical and microscopical features and both may develop at a young age
Whats also real are the health benefits that come with consistent use: improved digestion, more regular bowel movements, support for your immune system, better gut health, and weight management benefits when combined with a healthy diet and lifestyle