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The discovery of GLP-1 in 1986 provided the answer GLP-1 from the intestinal L-cells is the major incretin hormone responsible for up to ~5070% of post-meal insulin release in healthy individuals ( [75] )

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10.1016/S0002-9440(10)62288-2

Some users report nausea, appetite changes, increased freckles, and darkening of moles

For instance, it helps reduce inflammation, which is a key factor in many chronic pain conditions

People with severe kidney disease should use caution as limited safety data exists in this population