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Simultaneous GHRH-R and GHSR-1a activation produces additive GH pulse amplification a model for studying maximal pituitary GH secretory capacity while maintaining physiologic pulse architecture

Adiels 2008)

The resulting pentapeptide demonstrated potency comparable to GHRP-6 in multiple models: EC = 1.3 nmol/L in rat pituitary cells, ED = 80 nmol/kg in anesthetized rats, and ED = 2.3 nmol/kg in conscious swine

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Ipamorelin Acetate & Growth Hormone Ipamorelin Acetate is a peptide