A 2019 randomized controlled trial of lipotropic injections (methionine, inositol, choline, B12) versus saline placebo in 120 participants on ad libitum diets found 0.8 kg (1.76 pounds) difference at 12 weeks, not statistically significant (p=0.18) (Karbalay-Doust et al., Journal of Research in Medical Sciences , 2019)
Thiamin deficiency, on the other hand, can cause health concerns like swelling of the lower extremities, loss of muscle coordination, weight loss, lowered immunity and confusion
How about research papers
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Krause Analytical, a family-owned laboratory that Finnrick hires for much of its testing, also works with the F.D.A