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Glutathione is often referred to as the "master antioxidant" as it plays a central role in protecting our cells from oxidative stress and supporting our immune system

Glutathione is a critical antioxidant that protects cells from oxidative stress by neutralizing free radicals and reactive oxygen species (ROS)

In sickle cell anemia oxidative stress can trigger eryptosis and the release of red blood cell microparticles (RBC-MPs), which are small phospholipid-containing vesicles implicated in physiological processes such as hemostasis and potentially linked to macrovascular dysfunction

The analysis of SOD activity revealed variable responses depending on the brain region and treatment applied

Funding This study was supported by the Shanxi Provincial Basic Research Project of China (201901D111206) and Shanxi Provincial Health Commission Scientific Research Project of China (2020086)