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However, in NRVMs transfected with NR4a1 siRNA, oxidative respiration was significantly improved, and ATP production was increased (Fig
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This trial showed approximately 20% reduction in cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke compared to placebo
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These reduce melanin manufacturing within the skin, leading to a sluggish lightening effect
2.5 Recommended Dosage in Patients with Hepatic Impairment The recommended dosage of phentermine and topiramate extended-release capsules in patients with mild hepatic impairment (Child-Pugh 5 to 6) is the same as the recommended dosage in patients with normal hepatic function [see Use in Specific Populations (8.7), and Clinical Pharmacology (12.3)]
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