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Safety Profile : The tolerability of CT-388 appears to be favorable, with no treatment discontinuations reported due to adverse events and most side effects being mild to moderate in severity
Cuprizone autoimmune encephalitis (CAE) A variation of EAE where subdemyelinating doses of cuprizone are administered to mice (without exogenous myelin antigens), followed by an immune stimulation
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Cells 33 , 235241 (2012)
He Y, Ling Y, Zhang Z, Mertens RT, Cao Q, Xu X, et al
Donepezil attenuates inflammation and apoptosis in ulcerative colitis via regulating LRP1/AMPK/NF-B signaling
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