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GLP-1 receptors are expressed on various immune cells, including T lymphocytes and macrophages, and preclinical research has identified potential anti-inflammatory effects of GLP-1 signaling, but the clinical significance of these observations remains uncertain

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SURMOUNT-1 Eli Lilly 72 wk 20.9% 15 mg dose mean loss Mean body weight loss on the 15 mg maintenance dose at 72 weeks

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doi: 10.1093/eurheartj/ehy799 35 KoethRAWangZLevisonBSBuffaJAOrgESheehyBTet al

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