As of April 6, 2026, Foundayo will be available in the US for the self-pay price of $149$299 , depending on dose, through Eli Lillys LillyDirect pharmacy
Most side effects associated with oral semaglutide are mild and digestive in nature, particularly during the early stages of treatment or dose increases
Potential interactions with other medications also should be understood
These include: Paraesthesia (pins and needles) in hands and feet Peripheral neuropathy with numbness or altered sensation Difficulty walking or balance problems (ataxia) Memory problems and cognitive difficulties Mood changes, including depression or irritability In severe cases, confusion or dementia-like symptoms Other manifestations may include: Loss of appetite and unintentional weight loss Constipation Visual disturbances (rare, but can occur with optic neuropathy) Important: The neurological complications of B12 deficiency can progress even in the absence of anaemia, making early detection crucial
In our clinical practice, a baseline brain MRI is offered to patients with large CMN overlying the lower spine which may prompt referral to neurology or ongoing monitoring, although some parents choose to forego imaging given the limited available interventions
Monitoring and Follow-up Regular follow-ups for blood glucose and weight are significant for users who use semaglutide