If you have an MTHFR mutation you are a candidate for B12 shots
Certain vitamins, including B12, can affect people who have fatigue and a lack of energy
While some minor side effects like a bit of temporary soreness around the injection site can happen, its not very common
Individual responses to compounds can vary, and potential interactions with medications, pre-existing conditions, or other supplements should be evaluated by a qualified professional
(2) NNMT catalyzes the N-methylation of nicotinamide using SAM as a methyl donor, consuming both substrates in the process
Just look at the history of people with ME (myalgic encephalomyelitis) or with Long-Covid, and how they have been ill-diagnosed and not well treated, and you realize how mediocre the specific evaluation of many people with unexplained symptoms may have been