weekly semaglutide Weight loss with reduces pain, improves function in knee osteoarthritis 120 lbs down… and this

doi:10.1016/S0015-0282(01)01975-6

GLP-1 receptor agonists are contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

For some patients, using both makes sense

Mild Headaches or Dizziness Especially at higher doses or with first-time users

A reduction in size, number and function of mitochondria is associated with aging, and supporting mitochondria with essential nutrients like B12 and NAD can potentially slow and even reverse the aging process

MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus