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In most cases, patients don't report much discomfort since B12 is injected into the thigh, which is a less sensitive area of the body

This is a separate and still investigational line of research rather than an established use, and it should not be confused with the fat-loss mechanism that the bulk of the clinical work has focused on

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Clinical Obesity, 9(5), e12312

In topical laboratory models, concentrations between 1% and 2% are standard