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Luo D, Geng J, Li N, Carter KA, Shao S, Atilla-Gokcumen GE, et al

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Furthermore, another study indicated that the nephroprotective effect mediated through TLR-2 is in part attributed to activation of autophagy and knockout of TLR2 reduced expression of autophagy proteins and exacerbated renal dysfunction in the CP-induced AKI model (Liang et al., 2017)

the agency cited concerns over potential immune reactions, manufacturing impurities, and a lack of human safety data

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