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One consequence of this is impairment of the urea cycle, exacerbating hyperammonemia

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This imbalance impairs vasodilation, promotes vasoconstriction, and increases vascular permeability, creating a conducive environment for the infiltration of lipoproteins and immune cells into the arterial wall

According to Joseph Lambson, PharmD, director of the New Mexico Poison and Drug Information Center, symptoms of taking too much of a drug like Wegovy are similar to symptoms experienced at normal therapeutic doses, but more heightened: nausea, vomiting, headache, and dizziness

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You take certain medications: Long-term use of proton pump inhibitors (for acid reflux) or metformin (for diabetes) can interfere with B12 absorption