Yes, 1,000 mcg of vitamin B12 is safe for most people
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By inhibiting NNMT, it reduces the methylation of nicotinamide, which preserves the substrate pool feeding NAD+ salvage
But like any performance-enhancing compound, it demands respect
This is why you might notice that two people with seemingly identical lifestyles, including exercise and diet, can have wildly different outcomes
[15] [16] Standard NHS treatment protocols: Without neurological involvement: Hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, then maintenance injections every 2-3 months (lifelong if pernicious anaemia)