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Numerous studies demonstrating pleiotropic health promoting and antiage activity of the GHK-Cu peptide together with recent studies revealing gene regulating activity of GHK suggest that this compound may belong to a class of epigenetic modifiers capable of exhibiting broad protective and restorative actions, reducing harmful epigenetic changes caused by environmental perturbagens
The two peptides operate through largely complementary rather than overlapping mechanisms, which suggests a potentially additive or even synergistic effect in tissue repair models
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Mild side effects may include gastrointestinal discomfort or mild headaches
A dip in eGFR is evidence of a reduction in high pressure in the small blood vessels that filter the blood in the kidney
doi: 10.2174/1389200220666190426152830 212 OzakiM
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