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Simpler organisms like Drosophila and zebrafish offer unparalleled advantages for large-scale, high-throughput screening of potential CFTR modulators due to their low cost and rapid life cycle, although they cannot be used to study complex organ pathophysiology (Rosen et al., 2018
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For now, Strouhal and his colleagues dont recommend patients stop taking GLP-1 medications before undergoing PET-CT scans
Interest really took off in 2021 when the FDA approved semaglutide better known as Wegovy for chronic weight management, followed by Zepbound in late 2023
Semaglutide trials reported 24-29% constipation rates while tirzepatide trials showed 12-27%
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