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Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics

The limitations of this study include a short study period, lack of follow-up, lack of measurement of serum glutathione levels and the choice of cohort, which consisted of a young and healthy population

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Additionally glutathione plays a large role in liver function and detoxification

Jonsson T, Granfeldt Y, Ahren B, Branell UC, Palsson G, Hansson A,