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Reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: phosphorylcholine of oxidized phospholipids

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This is the same mechanism that turns stools black during BSS use, which patients should be counseled about upfront

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Eph/ephrin signalling The Eph proteins belong to the superfamily of receptor tyrosine kinases and include 14 human type 1 transmembrane protein members

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Triple agonism (GLP-1 + GIP + glucagon) is a real mechanistic advance, not just marketing but the full implications, especially for muscle mass, aren't confirmed yet

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More recently, the American Society of Anesthesiologists released a warning that patients taking Ozempic, Wegovy, and other weight loss medications should stop at least a week before they have elective surgery because of the risk they could throw up or regurgitate food while under anesthesia

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