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According to the American Diabetes Association (ADA), GLP-1 receptor agonists are now recommended as a first-line treatment in certain high-risk patients, especially those with established cardiovascular disease

The findings, published in BMJ Open Diabetes Research & Care , represent the first direct comparison between GLP-1s and metformin

Chronic stress elevates cortisol and inflammatory markers that worsen cardiovascular risk

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One small study, however, found that GLP-1 agonists were associated with significantly reduced pain, fatigue, and opioid dependency

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