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Common Side Effects and What to Expect Semaglutide is generally well tolerated, especially when the dose is increased gradually

That's similar to what's happening with insurance coverage for another weight loss drug, Wegovy

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GLP-1 Signaling at the Intersection of Metabolism and Reward The gut and brain communicate via the vagus nerve, so gut health directly impacts mood, anxiety, and neurodegenerative conditions

Some insurance plans do cover weight loss medications under specific circumstances (BMI over 30, or BMI over 27 with comorbidities), but coverage remains uncommon and varies significantly by plan

Chronic hyperglycemia can disrupt the balance of sex hormones and lead to menstrual irregularities