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206 Combined administration of shikonin and cisplatin increases Fe 2+ , ROS, and lipid peroxidation (LPO) levels and downregulates GPX4 in ovarian cancer cells, reducing cisplatin resistance by inducing ferroptosis
Drugs with narrow therapeutic windows (warfarin, levothyroxine, oral contraceptives, certain seizure medications) deserve clinician oversight
Moderate responders form the largest group, experiencing significant improvement between weeks 3-6
Its anti-inflammatory and antioxidant properties make it valuable for conditions where oxidative stress impairs recovery
Properly learning how to store glutathione injection vials is not a minor detail
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