"Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis"
These metabolic actions within the nervous system leading to the generation of ATP that is necessary for a) the synthesis of mitochondrial DNA neurons, b) for the formation of melanin axonal sheath, c) to provide the biochemical components of neurotransmission d) to maintain the constancy of the internal environment neuronal necessary to generate action potentials and allow transmission at synapses (Neurology, 1995, 45: 11-16)
Taking a large dose before drinking does not help stave off a hangover, as alcohol can reduce your absorption of B vitamins
Of course, older adults, people over age 50 in particular, tend to have the lowest B12 levels, though vegetarians and those who have undergone gastric bypass surgery are also at a higher risk
It's best to consult your doctor
PMID: 31338230