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A 20% relative risk reduction in MACE, including myocardial infarction, stroke, and cardiovascular death and a 30% relative risk reduction in hospitalizations for HF ( The VERTIS trial, involving 8246 patients with T2DM, compared ertugliflozin 5 mg or 15 mg daily to placebo for 3.5 years
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Both GLP-1 and its agonists (GLP-1RAs) have been identified for suppressing appetite, slowing gastric emptying time, and inducing fullness and satiety, thereby reducing caloric intake under ad libitum feeding conditions (139141)
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