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A review of GLP-1 agonist studies using the standard dose in high intracranial pressure reported: Patients should be counseled about the high likelihood of nausea and GI upset (diarrhea, vomiting, and constipation, delayed gastric emptying) especially in the first 48 weeks of therapy

Zofran works by blocking certain signals in the brain that trigger the feeling of nausea

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Several different types of GLP-1RAs are currently available

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