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The side effect profile at the 12mg dose includes nausea (28% of participants), diarrhea (23%), constipation (17%), and vomiting (12%)
Increases in blood vessel constriction by COX-2 inhibition can also lead to the hypertension and renal failure seen in some studies of non-selective and COX-2 selective NSAIDs (Conaghan 2012)
UV Damage Repair: Assists in reversing sun-induced discoloration when used consistently
Neurosci Biobehav Rev
It is also a key player in the function and development of brain and nerve cells
A weekly or twice-weekly injection visit creates a touchpoint weigh-ins, accountability, coaching
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