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doi: 10.1016/j.cmet.2017.08.022 67 KyriachenkoY.FalalyeyevaT.KorotkyiO.MolochekN.KobyliakN
In this cascade, ROS can stimulate the MAPK pathway, which causes cell proliferation through growth factors and K-ras
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This delayed transit can lead to constipation in 12-26% of patients, depending on dose and indication
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