Shortages have persisted since 2022
Consistent with these results, expression of PPG mRNA, a necessary precursor of GLP-1 production, is decreased in the NTS following seven days of cocaine abstinence, a time point associated with robust cocaine-seeking behavior in rats 8
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Location of itching also provides clues: localized itching at the injection site suggests a reaction to the injection itself, while generalized full-body itching is more likely tied to dehydration or skin changes from weight loss
Sublingual semaglutide offers another non-injection route
Nature 518 , 413416 (2015)