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Hepatocytes acquire transferrin-bound iron (TBI) and non-transferrin-bound iron (NTBI) via TFR1 and SLC39A14, respectively [25,26,27]

For instance, deficiencies in both could cause fatigue, but nerve pain was unique to B12, and bone pain was associated with a D deficiency

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Of these, Glu4.2 also co-expressed Ramp3 across all species (see Extended Data Figs