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Since ACTH signals the adrenal glands to produce cortisol, reducing ACTH translates to lower cortisol output
The VITAstir B12 being methylated (the active form) is the type my body needs due to an MTHFR gene
I also prescribed low-dose naltrexone, knowing from research that it could reduce the brain inflammation we see with POTS
On the other hand, GSH exerts a negative feedback inhibition on GCL
Park JM, Lee HJ, Sikiric P, Hahm KB
That distinction matters clinically
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