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Age Our bodies' absorption capacities for nutrients like vitamin B12 may decline with aging

The following drugs can cause some problems when taken together with Hydroxocobalamin Injection: chloramphenicol (an antibiotic) can reduce the effects of Hydroxocobalamin injection

For example, those with more severe deficiencies might need the higher end of this range

Vitamin B complex supplements can help prevent deficiencies in these cases

In June 2022 the UK medicines regulator updated its advice: the MHRA now lists low vitamin B12 as a common side effect of metformin, meaning it can affect up to one in ten people taking it

High activity of NNMT is also correlated with lower levels of glucose transporter 4 (GLUT4), which is vital for glucose uptake from the bloodstream into fat and muscle cells