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Oral glucagon-like peptide-1 receptor agonists and combinations of entero-pancreatic hormones as treatments for adults with type 2 diabetes: where are we now
But the excitement for peptides, including BPC-157, is very premature: For one thing, the evidence that proponents rave about comes from animal data, not human studies
Semaglutide solves both problems with three small changes to the native GLP-1(7-37) sequence
These medications act on GLP-1 and GIP receptors located throughout the body, not just in the digestive system
Identification of the peptide and receptors, however, does not by itself substantiate a functional relevance, but evidence for a physiological role of these receptor populations emerged 13 years later and will be discussed here
