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The docking analyses revealed that the positioning of the GSH-thiolate in relation to C-2 and O-3 of the docked substrates could enable an acidbase mechanism of dehydration or tautomerization, in which the GSH cofactor acts as a proton-relay system (Fig
A crucial role of alogliptin in inflammation, oxidative stress, and kidney damage by modulating MAP3K/JNK/c-Jun and SMAD3 pathways was established [41]
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