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Finally, the insertion of Sec at the UGA codon is facilitated through the recognition of a unique selenocysteine insertion sequence (SECIS) present in the three prime untranslated region (3-UTR) of mRNAs of seleno-GPxs by ribosomes with the help of SECIS binding protein (SBP)

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Exenatide and metformin express their anti-inflammatory effects on human monocytes/macrophages by the attenuation of MAPKs and NFB signaling

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However, it should not be ignored that natural small-molecule compounds may also cause kidney damage by inducing ferroptosis

Front Endocrinol (Lausanne) (2021) 12:721135