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While kojic acid is generally considered safer than hydroquinone, pregnant and breastfeeding women should consult their healthcare provider before use

Ozempic (semaglutide) was initially approved for the treatment of people with Type 2 diabetes, and it is part of a popular new class of medications known as glucagon-like peptide-1 receptor agonists (GLP-1RAs)

It is specifically contraindicated for individuals with: A personal or family history of medullary thyroid carcinoma (MTC), based on findings of thyroid C-cell tumours in animal studies Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Type 1 diabetes or diabetic ketoacidosis semaglutide is not designed for this purpose Pregnancy, or plans to become pregnant within the next 2 months (semaglutide should be discontinued at least 2 months before attempting conception) Age under 12 years (Wegovy is approved from age 12 only for severe obesity, under specialist supervision) Additional caution is needed for patients with a history of pancreatitis, gallbladder disease, diabetic retinopathy, or significant kidney impairment these patients require closer monitoring throughout treatment

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Differential Metabotypes in Synovial Fibroblasts and Synovial Fluid in Hip Osteoarthritis Patients Support Inflammatory Responses

Accessed March 30, 2026